diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index 9528bf3b8..5d0a57d9b 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -12,6 +12,9 @@ concurrency:
   group: build-${{ github.ref }}
   cancel-in-progress: true
 
+env:
+  C2_ENABLE_LTO: ${{ github.ref == 'refs/heads/master' }}
+
 jobs:
   build:
     runs-on: ${{ matrix.os }}
@@ -20,17 +23,25 @@ jobs:
         os: [windows-latest, ubuntu-20.04, macos-latest]
         qt-version: [5.15.2, 5.12.12]
         pch: [true]
+        force-lto: [false]
         include:
           - os: ubuntu-20.04
             qt-version: 5.15.2
             pch: false
+            force-lto: true
       fail-fast: false
 
     steps:
+      - name: Force LTO
+        if: matrix.force-lto == true
+        run: |
+            echo "C2_ENABLE_LTO=ON" >> "$GITHUB_ENV"
+        shell: bash
+
       - name: Set environment variables for windows-latest
         if: matrix.os == 'windows-latest'
         run: |
-            echo "vs_version=2022" >> $GITHUB_ENV
+            echo "vs_version=2022" >> "$GITHUB_ENV"
         shell: bash
 
       - uses: actions/checkout@v3
@@ -80,7 +91,12 @@ jobs:
             mkdir build
             cd build
             conan install ..  -b missing
-            cmake -G"NMake Makefiles" -DCMAKE_BUILD_TYPE=Release -DUSE_CONAN=ON ..
+            cmake `
+                -G"NMake Makefiles" `
+                -DCMAKE_BUILD_TYPE=Release `
+                -DUSE_CONAN=ON `
+                -DCHATTERINO_LTO="$Env:C2_ENABLE_LTO" `
+                ..
             set cl=/MP
             nmake /S /NOLOGO
             windeployqt bin/chatterino.exe --release --no-compiler-runtime --no-translations --no-opengl-sw --dir Chatterino2/
@@ -137,8 +153,9 @@ jobs:
               -DPAJLADA_SETTINGS_USE_BOOST_FILESYSTEM=On \
               -DUSE_PRECOMPILED_HEADERS=${{ matrix.pch }} \
               -DCMAKE_EXPORT_COMPILE_COMMANDS=On \
+              -DCHATTERINO_LTO="$C2_ENABLE_LTO" \
               ..
-            make -j$(nproc)
+            make -j"$(nproc)"
         shell: bash
 
       - name: clang-tidy review
@@ -203,8 +220,9 @@ jobs:
                 -DCMAKE_OSX_DEPLOYMENT_TARGET=10.15 \
                 -DOPENSSL_ROOT_DIR=/usr/local/opt/openssl \
                 -DUSE_PRECOMPILED_HEADERS=${{ matrix.pch }} \
+                -DCHATTERINO_LTO="$C2_ENABLE_LTO" \
                 ..
-            make -j$(sysctl -n hw.logicalcpu)
+            make -j"$(sysctl -n hw.logicalcpu)"
         shell: bash
 
       - name: Package (MacOS)
diff --git a/CHANGELOG.md b/CHANGELOG.md
index 2590791c6..79fd7d503 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -17,6 +17,7 @@
 - Dev: Remove protocol from QApplication's Organization Domain (so changed from `https://www.chatterino.com` to `chatterino.com`). (#4256)
 - Dev: Ignore `WM_SHOWWINDOW` hide events, causing fewer attempted rescales. (#4198)
 - Dev: Migrated to C++ 20 (#4252, #4257)
+- Dev: Enable LTO for main branch builds. (#4258)
 
 ## 2.4.0
 
diff --git a/CMakeLists.txt b/CMakeLists.txt
index 46a7ecb36..9372d7de1 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -20,9 +20,18 @@ option(USE_PRECOMPILED_HEADERS "Use precompiled headers" ON)
 option(BUILD_WITH_QT6 "Use Qt6 instead of default Qt5" OFF)
 option(CHATTERINO_GENERATE_COVERAGE "Generate coverage files" OFF)
 option(BUILD_SHARED_LIBS "" OFF)
+option(CHATTERINO_LTO "Enable LTO for all targets" ON)
 
 option(USE_CONAN "Use conan" OFF)
 
+if(CHATTERINO_LTO)
+    include(CheckIPOSupported)
+    check_ipo_supported(RESULT CHATTERINO_ENABLE_LTO OUTPUT IPO_ERROR)
+    message(STATUS "LTO: Enabled (Supported: ${CHATTERINO_ENABLE_LTO})")
+else()
+    message(STATUS "LTO: Disabled")
+endif()
+
 if (BUILD_WITH_QT6)
     set(MAJOR_QT_VERSION "6")
 else()
diff --git a/src/CMakeLists.txt b/src/CMakeLists.txt
index 34abbff79..3f282b898 100644
--- a/src/CMakeLists.txt
+++ b/src/CMakeLists.txt
@@ -665,6 +665,12 @@ if (BUILD_APP)
                 DESTINATION share/icons/hicolor/256x256/apps
                 )
     endif ()
+
+    if(CHATTERINO_ENABLE_LTO)
+        message(STATUS "Enabling LTO for ${EXECUTABLE_PROJECT}")
+        set_property(TARGET ${EXECUTABLE_PROJECT}
+            PROPERTY INTERPROCEDURAL_OPTIMIZATION TRUE)
+    endif()
 endif ()
 
 if (USE_PRECOMPILED_HEADERS)
@@ -843,3 +849,9 @@ else ()
         )
     endif()
 endif ()
+
+if(CHATTERINO_ENABLE_LTO)
+    message(STATUS "Enabling LTO for ${LIBRARY_PROJECT}")
+    set_property(TARGET ${LIBRARY_PROJECT}
+                 PROPERTY INTERPROCEDURAL_OPTIMIZATION TRUE)
+endif()
diff --git a/tests/CMakeLists.txt b/tests/CMakeLists.txt
index 8887753dd..2ba34a685 100644
--- a/tests/CMakeLists.txt
+++ b/tests/CMakeLists.txt
@@ -46,6 +46,12 @@ set_target_properties(${PROJECT_NAME}
     RUNTIME_OUTPUT_DIRECTORY_RELWITHDEBINFO "${CMAKE_BINARY_DIR}/bin"
     )
 
+if(CHATTERINO_ENABLE_LTO)
+    message(STATUS "Enabling LTO for ${PROJECT_NAME}")
+    set_property(TARGET ${PROJECT_NAME}
+        PROPERTY INTERPROCEDURAL_OPTIMIZATION TRUE)
+endif()
+
 # gtest_add_tests manages to discover the tests because it looks through the source files
 # HOWEVER, it fails to run, because we have some bug that causes the QApplication exit to stall when no network requests have been made.
 # ctest runs each test individually, so for now we require that testers just run the ./bin/chatterino-test binary without any filters applied